Assay Detail
Functional
CHEMBL5229416
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Antibacterial activity against Escherichia coli ATCC 25922 assessed as inhibition of bacterial growth at 6 to 12 hrs by dilution method
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Escherichia coli |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Screening for Cyclotides in Sri Lankan Medicinal Plants: Discovery, Characterization, and Bioactivity Screening of Cyclotides from <i>Geophila repens</i>.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.40 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5271959 | — | — | 1 | 5.40 |
| CHEMBL4285275 | — | — | 1 | - |
| CHEMBL4211294 | — | — | 1 | - |
| CHEMBL5283188 | — | — | 1 | - |
| CHEMBL5291484 | — | — | 1 | - |
| CHEMBL5290770 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5271959 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL4285275 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4211294 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL5283188 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL5291484 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL5290770 | — | IC50 | > | 10000.0 | nM | - |