Assay Detail
Toxicity
CHEMBL5230042
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Cytotoxicity against LPS-stimulated mouse RAW264.7 cells assessed as cell growth inhibition preincubated for 15 mins followed by LPS stimulation and measured after 20 hrs by CCK-8 assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Mus musculus |
| Cell Type | RAW264.7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Anti-inflammatory Quinoline Alkaloids from the Roots of <i>Waltheria indica</i>.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.52 | 4.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5267196 | — | — | 1 | 4.59 |
| CHEMBL3342751 | — | — | 1 | 4.49 |
| CHEMBL5291228 | — | — | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5267196 | — | IC50 | = | 25900.0 | nM | 4.59 |
| CHEMBL3342751 | — | IC50 | = | 32200.0 | nM | 4.49 |
| CHEMBL5291228 | — | IC50 | = | 33300.0 | nM | 4.48 |