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Assay Detail

CHEMBL5230537

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human MOLM-14 cells assessed as cell growth inhibition measured after 72 hrs by cell titer-Blue assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MOLM-14
Confidence 1 — Organism
Curated By Autocuration

Target

MOLM-14 (CHEMBL3706570)
Type CELL-LINE
Organism Homo sapiens

Publication

Small-Molecule Fms-like Tyrosine Kinase 3 Inhibitors: An Attractive and Efficient Method for the Treatment of Acute Myeloid Leukemia.
Zhong Y, Qiu RZ, Sun SL, Zhao C, Fan TY, Chen M, Li NG, Shi ZH.
J Med Chem (2020) 63 : 12403 -12428
PubMed 32659083 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.30 9.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5284731 1 9.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5284731 IC50 = 0.5 nM 9.30