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Assay Detail

CHEMBL5230544

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity activity against human 697 cells assessed as reduction cell viability at 50 uM incubated for 48 hrs by ATP-glo assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type 697
Confidence 1 — Organism
Curated By Autocuration

Target

697 (CHEMBL2366253)
Type CELL-LINE
Organism Homo sapiens

Publication

Small-Molecule Fms-like Tyrosine Kinase 3 Inhibitors: An Attractive and Efficient Method for the Treatment of Acute Myeloid Leukemia.
Zhong Y, Qiu RZ, Sun SL, Zhao C, Fan TY, Chen M, Li NG, Shi ZH.
J Med Chem (2020) 63 : 12403 -12428
PubMed 32659083 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.57 8.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3326006 1 8.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3326006 IC50 = 2.7 nM 8.57