Assay Detail
Binding
CHEMBL5230853
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of EGFR (unknown origin) by microplate reader analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel quinazoline-based EGFR kinase inhibitors: A review focussing on SAR and molecular docking studies (2015-2019).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.75 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5282557 | — | — | 1 | 6.80 |
| CHEMBL553 | ERLOTINIB | 4.0 | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5282557 | — | IC50 | = | 157.63 | nM | 6.80 |
| CHEMBL553 | ERLOTINIB | IC50 | = | 201.34 | nM | 6.70 |