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Assay Detail

CHEMBL5230857

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against rat H9c2 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Rattus norvegicus
Cell Type H9c2
Confidence 1 — Organism
Curated By Autocuration

Target

H9c2 (CHEMBL614576)
Type CELL-LINE
Organism Rattus norvegicus

Publication

Novel quinazoline-based EGFR kinase inhibitors: A review focussing on SAR and molecular docking studies (2015-2019).
Bhatia P, Sharma V, Alam O, Manaithiya A, Alam P, Kahksha, Alam MT, Imran M.
Eur J Med Chem (2020) 204 : 112640 -112640
PubMed 32739648 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5282557 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5282557 IC50 = 10.0 nM 8.00