Assay Detail
Functional
CHEMBL5230864
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human CNE cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CNE |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel quinazoline-based EGFR kinase inhibitors: A review focussing on SAR and molecular docking studies (2015-2019).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.80 | 5.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5279000 | — | — | 1 | 5.68 |
| CHEMBL939 | GEFITINIB | 4.0 | 1 | 4.63 |
| CHEMBL418068 | RHEIN | — | 1 | 4.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5279000 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL939 | GEFITINIB | IC50 | = | 23500.0 | nM | 4.63 |
| CHEMBL418068 | RHEIN | IC50 | = | 81700.0 | nM | 4.09 |