Assay Detail
Functional
CHEMBL5230876
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human A-431 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A-431 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel quinazoline-based EGFR kinase inhibitors: A review focussing on SAR and molecular docking studies (2015-2019).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.66 | 5.78 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5286575 | — | — | 1 | 5.78 |
| CHEMBL939 | GEFITINIB | 4.0 | 1 | 5.53 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5286575 | — | IC50 | = | 1680.0 | nM | 5.78 |
| CHEMBL939 | GEFITINIB | IC50 | = | 2980.0 | nM | 5.53 |