Assay Detail
Functional
CHEMBL5231012
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Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth by SRB assay
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hydroxamic acid hybrids as the potential anticancer agents: An Overview.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| GI50 | 3 | - | - |
| IC50 | 1 | 7.54 | 7.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3329991 | — | — | 1 | 7.54 |
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | - |
| CHEMBL5283979 | — | — | 1 | - |
| CHEMBL5287701 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3329991 | — | IC50 | = | 29.0 | nM | 7.54 |
| CHEMBL98 | VORINOSTAT | GI50 | > | 410.0 | nM | - |
| CHEMBL5283979 | — | GI50 | = | 20.0 | nM | - |
| CHEMBL5287701 | — | GI50 | = | 20.0 | nM | - |