Assay Detail
Functional
CHEMBL5231183
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human A-375 cells assessed as inhibition of cell viability
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A-375 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Systemic review on B-Raf<sup>V600E</sup> mutation as potential therapeutic target for the treatment of cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.68 | 6.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5271555 | — | — | 1 | 6.43 |
| CHEMBL4216588 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5271555 | — | IC50 | = | 370.0 | nM | 6.43 |
| CHEMBL4216588 | — | IC50 | = | 12000.0 | nM | 4.92 |