Assay Detail
Functional
CHEMBL5231533
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Antiviral activity against RSV infected in human HEp-2 cells assessed as inhibition of viral induced cytopathic effect by CPE assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Respiratory syncytial virus |
| Cell Type | HEp-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Respiratory syncytial virus (CHEMBL612679) ↗| Type | ORGANISM |
| Organism | Respiratory syncytial virus |
Publication
Antiviral potential of natural products from marine microbes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.67 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | 7.10 |
| CHEMBL5286194 | — | — | 1 | 6.92 |
| CHEMBL4442474 | — | — | 1 | 4.52 |
| CHEMBL5277335 | — | — | 1 | 4.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1643 | RIBAVIRIN | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL5286194 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL4442474 | — | IC50 | = | 30250.0 | nM | 4.52 |
| CHEMBL5277335 | — | IC50 | = | 72010.0 | nM | 4.14 |