Assay Detail
Functional
CHEMBL5231730
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Immunosuppressive activity in BDF1 mouse Splenocyte assessed as inhibition of concanavalin A induced T-cell proliferation incubated for 72 hrs by [3H]-thymidine incorporation based liquid scintillation counter analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | Splenocyte |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Research progress of mTOR inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.46 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4287849 | — | — | 1 | 8.70 |
| CHEMBL4279511 | — | — | 1 | 8.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4287849 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL4279511 | — | IC50 | = | 6.0 | nM | 8.22 |