Assay Detail
Binding
CHEMBL5231981
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of DNA topoisomerase 1 (unknown origin) at 50 uM measured by agar gel electrophoresis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A review: Biologically active 3,4-heterocycle-fused coumarins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.42 | 7.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1946917 | — | — | 1 | 7.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1946917 | — | IC50 | = | 38.5 | nM | 7.42 |