Assay Detail
Functional
CHEMBL5231982
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human NCI-H69AR cells assessed as reduction in cell viability by SRB assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | H69AR |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A review: Biologically active 3,4-heterocycle-fused coumarins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.86 | 5.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4437011 | — | — | 1 | 5.37 |
| CHEMBL44657 | ETOPOSIDE | 4.0 | 1 | 4.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4437011 | — | IC50 | = | 4300.0 | nM | 5.37 |
| CHEMBL44657 | ETOPOSIDE | IC50 | = | 45900.0 | nM | 4.34 |