Assay Detail
Binding
CHEMBL5232276
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Inhibition of MMP-9 (unknown origin) assessed as inhibition constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibitors of gelatinases (MMP-2 and MMP-9) for the management of hematological malignancies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.88 | 7.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5175770 | — | — | 1 | 7.23 |
| CHEMBL261932 | TANOMASTAT | 2.0 | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5175770 | — | Ki | = | 59.0 | nM | 7.23 |
| CHEMBL261932 | TANOMASTAT | Ki | = | 301.0 | nM | 6.52 |