Assay Detail
Binding
CHEMBL5233435
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of BRD4 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A concise review of recent advances in anti-heart failure targets and its small molecules inhibitors in recent years.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.87 | 7.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1957266 | — | — | 1 | 7.11 |
| CHEMBL2393130 | APABETALONE | 3.0 | 1 | 6.85 |
| CHEMBL2179387 | — | — | 1 | 6.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1957266 | — | IC50 | = | 77.0 | nM | 7.11 |
| CHEMBL2393130 | APABETALONE | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL2179387 | — | IC50 | = | 220.0 | nM | 6.66 |