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Assay Detail

CHEMBL5233531

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Functional
Antiproliferative activity against human KG-1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT colorimetric assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type KG-1
Confidence 1 — Organism
Curated By Autocuration

Target

KG-1 (CHEMBL612264)
Type CELL-LINE
Organism Homo sapiens

Publication

Recent advance in the development of novel, selective and potent FGFR inhibitors.
Liu FT, Li NG, Zhang YM, Xie WC, Yang SP, Lu T, Shi ZH.
Eur J Med Chem (2020) 186 : 111884 -111884
PubMed 31761386 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.84 7.84

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4062877 1 7.84

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4062877 IC50 = 14.5 nM 7.84