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Assay Detail

CHEMBL5233544

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Binding
Binding affinity to STAT3 (unknown origin) by surface plasmon resonance assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Signal transducer and activator of transcription 3 (CHEMBL4026)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Revisiting signal transducer and activator of transcription 3 (STAT3) as an anticancer target and its inhibitor discovery: Where are we and where should we go?
Huang Q, Zhong Y, Dong H, Zheng Q, Shi S, Zhu K, Qu X, Hu W, Zhang X, Wang Y.
Eur J Med Chem (2020) 187 : 111922 -111922
PubMed 31810784 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.30 6.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1829876 1 6.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1829876 Kd = 504.0 nM 6.30