Assay Detail
Binding
CHEMBL5234032
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human EGFR L858R/T790M mutant (696 to 1022 residues) expressed in insect sf9 cells in presence of ATP by HTRF assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Allosteric inhibitors of the STAT3 signaling pathway.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.59 | 9.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4443062 | — | — | 1 | 9.59 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4443062 | — | IC50 | = | 0.26 | nM | 9.59 |