Assay Detail
Functional
CHEMBL5234343
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Antimalarial activity against Plasmodium
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A medicinal chemistry perspective of drug repositioning: Recent advances and challenges in drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.45 | 7.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1017 | TELMISARTAN | 4.0 | 1 | 7.60 |
| CHEMBL1200667 | ENCLOMIPHENE CITRATE | 3.0 | 1 | 6.66 |
| CHEMBL5279304 | — | — | 1 | 6.54 |
| CHEMBL160 | CYCLOSPORINE | 4.0 | 1 | 5.77 |
| CHEMBL1200795 | CLEMASTINE FUMARATE | 4.0 | 1 | 5.66 |
| CHEMBL1503 | OMEPRAZOLE | 4.0 | 1 | - |
| CHEMBL1116 | RALOXIFENE HYDROCHLORIDE | 4.0 | 1 | - |
| CHEMBL935 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1017 | TELMISARTAN | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL1200667 | ENCLOMIPHENE CITRATE | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL5279304 | — | IC50 | = | 290.0 | nM | 6.54 |
| CHEMBL160 | CYCLOSPORINE | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL1200795 | CLEMASTINE FUMARATE | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL1503 | OMEPRAZOLE | IC50 | < | 1000.0 | nM | - |
| CHEMBL1116 | RALOXIFENE HYDROCHLORIDE | IC50 | < | 500.0 | nM | - |
| CHEMBL935 | — | IC50 | < | 500.0 | nM | - |