Assay Detail
Binding
CHEMBL5234403
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Inhibition of human recombinant ABHD6
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Therapeutic potential of targeting α/β-Hydrolase domain-containing 6 (ABHD6).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 8.58 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5274434 | — | — | 1 | 8.70 |
| CHEMBL3906477 | — | — | 1 | 8.60 |
| CHEMBL4279328 | — | — | 1 | 8.60 |
| CHEMBL3895863 | — | — | 1 | 8.55 |
| CHEMBL4581240 | — | — | 1 | 8.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5274434 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL3906477 | — | IC50 | = | 2.5 | nM | 8.60 |
| CHEMBL4279328 | — | IC50 | = | 2.5 | nM | 8.60 |
| CHEMBL3895863 | — | IC50 | = | 2.8 | nM | 8.55 |
| CHEMBL4581240 | — | IC50 | = | 3.6 | nM | 8.44 |