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Assay Detail

CHEMBL5234599

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anticancer activity against human HCT-116 cells assessed as cell growth inhibition
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HCT-116
Confidence 1 — Organism
Curated By Autocuration

Target

HCT-116 (CHEMBL394)
Type CELL-LINE
Organism Homo sapiens

Publication

Resveratrol - A comprehensive review of recent advances in anticancer drug design and development.
Ahmadi R, Ebrahimzadeh MA.
Eur J Med Chem (2020) 200 : 112356 -112356
PubMed 32485531 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 6 5.31 5.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL296411 TRISMETHOXYRESVERATROL 1 5.96
CHEMBL87982 1 5.96
CHEMBL69863 PICEATANNOL 1 5.30
CHEMBL5276463 1 5.30
CHEMBL165 RESVERATROL 3.0 1 4.71
CHEMBL87333 CIS-RESVERATROL 1 4.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL296411 TRISMETHOXYRESVERATROL IC50 = 1100.0 nM 5.96
CHEMBL87982 IC50 = 1100.0 nM 5.96
CHEMBL69863 PICEATANNOL IC50 = 5000.0 nM 5.30
CHEMBL5276463 IC50 = 5000.0 nM 5.30
CHEMBL165 RESVERATROL IC50 = 19400.0 nM 4.71
CHEMBL87333 CIS-RESVERATROL IC50 = 25100.0 nM 4.60