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Assay Detail

CHEMBL5234790

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of LOX (unknown origin) at 1 uM
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Polyunsaturated fatty acid lipoxygenase ALOX15 (CHEMBL2903)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Recent advancements in the development of heterocyclic anti-inflammatory agents.
Sharma S, Kumar D, Singh G, Monga V, Kumar B.
Eur J Med Chem (2020) 200 : 112438 -112438
PubMed 32485533 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.02 5.02

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL131820 1 5.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL131820 IC50 = 9510.0 nM 5.02