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Assay Detail

CHEMBL5234935

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Functional
Induction of apoptosis in human RS4-11 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type RS4-11
Confidence 1 — Organism
Curated By Autocuration

Target

RS4-11 (CHEMBL2366159)
Type CELL-LINE
Organism Homo sapiens

Publication

Single and dual target inhibitors based on Bcl-2: Promising anti-tumor agents for cancer therapy.
Liu T, Wu Z, He Y, Xiao Y, Xia C.
Eur J Med Chem (2020) 201 : 112446 -112446
PubMed 32563811 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.52 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3137309 VENETOCLAX 4.0 1 8.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3137309 VENETOCLAX EC50 = 3.0 nM 8.52