Assay Detail
Toxicity
CHEMBL5235226
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Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Mus musculus |
| Cell Type | RAW264.7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Anti-inflammatory activity of naturally occuring diarylheptanoids - A review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.60 | 5.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5276513 | — | — | 1 | 5.05 |
| CHEMBL330645 | PLATYPHYLLENONE | — | 1 | 4.51 |
| CHEMBL2346808 | — | — | 1 | 4.44 |
| CHEMBL464274 | DEHYDROHIRSUTANONOL | — | 1 | 4.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5276513 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL330645 | PLATYPHYLLENONE | IC50 | = | 30700.0 | nM | 4.51 |
| CHEMBL2346808 | — | IC50 | = | 36400.0 | nM | 4.44 |
| CHEMBL464274 | DEHYDROHIRSUTANONOL | IC50 | = | 39000.0 | nM | 4.41 |