Assay Detail
Binding
CHEMBL5235940
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Inhibition of mushroom tyrosinase monophenolase activity
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
An overview of hydroxypyranone and hydroxypyridinone as privileged scaffolds for novel drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.35 | 5.80 |
| IC5 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5273014 | — | — | 1 | 5.80 |
| CHEMBL4572517 | — | — | 1 | 4.90 |
| CHEMBL5283180 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5273014 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL4572517 | — | IC50 | = | 12600.0 | nM | 4.90 |
| CHEMBL5283180 | — | IC5 | = | 2.04 | uM | - |