Assay Detail
Binding
CHEMBL5236038
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 mins
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | CHO |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Oxidative Metabolism as a Modulator of Kratom's Biological Actions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.37 | 7.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5276728 | — | — | 1 | 7.47 |
| CHEMBL4546925 | — | — | 1 | 7.11 |
| CHEMBL292521 | — | — | 1 | 6.67 |
| CHEMBL4859858 | — | — | 1 | 6.24 |
| CHEMBL4848517 | — | — | 1 | 6.18 |
| CHEMBL5287921 | — | — | 1 | 5.78 |
| CHEMBL56717 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5276728 | — | Ki | = | 34.1 | nM | 7.47 |
| CHEMBL4546925 | — | Ki | = | 78.6 | nM | 7.11 |
| CHEMBL292521 | — | Ki | = | 216.2 | nM | 6.67 |
| CHEMBL4859858 | — | Ki | = | 578.23 | nM | 6.24 |
| CHEMBL4848517 | — | Ki | = | 665.7 | nM | 6.18 |
| CHEMBL5287921 | — | Ki | = | 1674.7 | nM | 5.78 |
| CHEMBL56717 | — | Ki | = | 6902.0 | nM | 5.16 |