Mu-type opioid receptor · SINGLE PROTEIN · Mus musculus
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt P42866. Use UniProt P42866 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P42866 as the stable identity anchor, then attach disease evidence before program review.
Mu-type opioid receptor
Review this target as Mu-type opioid receptor, mapped to UniProt P42866. Sequence length is 398 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Mu-type opioid receptor as ChEMBL target CHEMBL2858, mapped to UniProt P42866. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Mu-type opioid receptor is the right protein anchor across sources, using UniProt P42866 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Mu-type opioid receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P42866 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Mu-type opioid receptor |
| UniProt Accession | P42866 |
| Component Type | Protein |
| Sequence Length | 398 aa |
Mu-type opioid receptor
Review this target as Mu-type opioid receptor, mapped to UniProt P42866. Sequence length is 398 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2311157 | 10.62 | Ki | 0.024 | Preclinical |
| CHEMBL2016678 | 10.31 | Ki | 0.049 | Preclinical |
| CHEMBL3215908 | 10.28 | Ki | 0.052 | Preclinical |
| CHEMBL3339374 | 10.28 | Ki | 0.052 | Preclinical |
| CHEMBL121403 | 10.22 | Ki | 0.06 | Preclinical |
| CHEMBL4128945 | 10.15 | IC50 | 0.07 | Preclinical |
| CHEMBL3216338 | 10.12 | Ki | 0.075 | Preclinical |
| CHEMBL338510 | 10.1 | Ki | 0.08 | Preclinical |
| CHEMBL3216579 | 10.09 | Ki | 0.081 | Preclinical |
| CHEMBL2016675 | 10.01 | Ki | 0.097 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 53 | 147 | 7.5 |
| tissue-based format | 29 | 23 | 7.6 |
| assay format | 25 | 16 | 7.0 |
| organism-based format | 10 | 0 | — |
| cell membrane format | 8 | 62 | 8.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 30 | 151 | 7.8 |
| cell membrane format | 26 | 172 | 8.2 |
| cell-based format | 26 | 251 | 8.5 |
| tissue-based format | 20 | 90 | 7.9 |
| assay format | 14 | 119 | 7.7 |
| organism-based format | 2 | 3 | 9.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 1 | 0 | — |