Assay Detail
Binding
CHEMBL5236040
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 mins
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | CHO |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Oxidative Metabolism as a Modulator of Kratom's Biological Actions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 5.77 | 7.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5276728 | — | — | 1 | 7.31 |
| CHEMBL4546925 | — | — | 1 | 5.94 |
| CHEMBL292521 | — | — | 1 | 5.72 |
| CHEMBL5287921 | — | — | 1 | 5.49 |
| CHEMBL4848517 | — | — | 1 | 5.47 |
| CHEMBL56717 | — | — | 1 | 5.38 |
| CHEMBL4859858 | — | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5276728 | — | Ki | = | 49.1 | nM | 7.31 |
| CHEMBL4546925 | — | Ki | = | 1154.3 | nM | 5.94 |
| CHEMBL292521 | — | Ki | = | 1882.4 | nM | 5.72 |
| CHEMBL5287921 | — | Ki | = | 3239.3 | nM | 5.49 |
| CHEMBL4848517 | — | Ki | = | 3395.0 | nM | 5.47 |
| CHEMBL56717 | — | Ki | = | 4143.0 | nM | 5.38 |
| CHEMBL4859858 | — | Ki | = | 7947.0 | nM | 5.10 |