Assay Detail
Binding
CHEMBL5236435
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Binding affinity to mouse PCSK9
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Proprotein convertase subtilisin/kexin type 9 (CHEMBL5291514) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Recent Update on the Development of PCSK9 Inhibitors for Hypercholesterolemia Treatment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 8.34 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5271747 | — | — | 1 | 9.00 |
| CHEMBL5278292 | — | — | 1 | 7.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5271747 | — | Kd | = | 1.0 | nM | 9.00 |
| CHEMBL5278292 | — | Kd | = | 21.0 | nM | 7.68 |