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Assay Detail

CHEMBL5236872

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against CHO cells assessed as reduction in cell proliferation by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cricetulus griseus
Cell Type CHO
Confidence 1 — Organism
Curated By Autocuration

Target

CHO (CHEMBL613853)
Type CELL-LINE
Organism Cricetulus griseus

Publication

Furazans in Medicinal Chemistry.
Mancini RS, Barden CJ, Weaver DF, Reed MA.
J Med Chem (2021) 64 : 1786 -1815
PubMed 33569941 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 5.64 5.73

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL326705 1 5.73
CHEMBL5278835 1 5.54

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL326705 EC50 = 1850.0 nM 5.73
CHEMBL5278835 EC50 = 2850.0 nM 5.54