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Assay Detail

CHEMBL5237298

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against HIV infected in human C8166 cells
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus
Cell Type C8166
Confidence 1 — Organism
Curated By Autocuration

Target

Human immunodeficiency virus (CHEMBL613758)
Type ORGANISM
Organism Human immunodeficiency virus

Publication

Andrographolide and its derivatives: Current achievements and future perspectives.
Zhang H, Li S, Si Y, Xu H.
Eur J Med Chem (2021) 224 : 113710 -113710
PubMed 34315039 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.37 5.63

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL186141 ANDROGRAPHOLIDE 3.0 2 5.63

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL186141 ANDROGRAPHOLIDE IC50 = 2320.0 nM 5.63
CHEMBL186141 ANDROGRAPHOLIDE IC50 = 7900.0 nM 5.10