Assay Detail
Functional
CHEMBL5237433
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Antiproliferative activity against human PC-9 cells assessed as reduction in cell viability
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-9 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Pharmacological inhibition of KDM5A for cancer treatment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 5.71 | 6.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5287732 | — | — | 1 | 6.02 |
| CHEMBL5286372 | — | — | 1 | 6.02 |
| CHEMBL4059597 | — | — | 1 | 5.82 |
| CHEMBL4088737 | — | — | 1 | 5.80 |
| CHEMBL5280725 | — | — | 1 | 5.30 |
| CHEMBL4454253 | — | — | 1 | 5.28 |
| CHEMBL4083572 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5287732 | — | EC50 | = | 960.0 | nM | 6.02 |
| CHEMBL5286372 | — | EC50 | = | 960.0 | nM | 6.02 |
| CHEMBL4059597 | — | EC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL4088737 | — | EC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL5280725 | — | EC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL4454253 | — | EC50 | = | 5200.0 | nM | 5.28 |
| CHEMBL4083572 | — | EC50 | > | 30000.0 | nM | - |