Assay Detail
Binding
CHEMBL5237444
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of KDM5B (unknown origin ) by TR-FRET assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Pharmacological inhibition of KDM5A for cancer treatment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.04 | 7.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4088737 | — | — | 1 | 7.25 |
| CHEMBL3188597 | — | — | 1 | 6.77 |
| CHEMBL5272568 | — | — | 1 | 5.11 |
| CHEMBL5274906 | — | — | 1 | 5.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4088737 | — | IC50 | = | 56.0 | nM | 7.25 |
| CHEMBL3188597 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL5272568 | — | IC50 | = | 7700.0 | nM | 5.11 |
| CHEMBL5274906 | — | IC50 | = | 9700.0 | nM | 5.01 |