Assay Detail
Binding
CHEMBL5237446
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Inhibition of KDM5A (unknown origin ) demethylase activity
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Pharmacological inhibition of KDM5A for cancer treatment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.50 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5287732 | — | — | 1 | 6.80 |
| CHEMBL4083572 | — | — | 1 | 6.58 |
| CHEMBL5276550 | — | — | 1 | 6.50 |
| CHEMBL5283892 | — | — | 1 | 6.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5287732 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL4083572 | — | IC50 | = | 260.0 | nM | 6.58 |
| CHEMBL5276550 | — | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL5283892 | — | IC50 | = | 770.0 | nM | 6.11 |