Assay Detail
Binding
CHEMBL5237783
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of porcine brain tubulin polymerization preincubated for 1 mins followed by GTP addition and measured for 60 mins at 1 min interval by fluorescence assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Bioactive Aurones, Indanones, and Other Hemiindigoid Scaffolds: Medicinal Chemistry and Photopharmacology Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.55 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2018039 | — | — | 1 | 5.82 |
| CHEMBL3818930 | — | — | 1 | 5.70 |
| CHEMBL3740269 | — | — | 1 | 5.12 |
| CHEMBL107 | COLCHICINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2018039 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL3818930 | — | IC50 | = | 1990.0 | nM | 5.70 |
| CHEMBL3740269 | — | IC50 | = | 7560.0 | nM | 5.12 |
| CHEMBL107 | COLCHICINE | IC50 | = | 10.0 | nM | - |