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Assay Detail

CHEMBL5237791

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by sulforhodamine assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HCT-116
Confidence 1 — Organism
Curated By Autocuration

Target

HCT-116 (CHEMBL394)
Type CELL-LINE
Organism Homo sapiens

Publication

Bioactive Aurones, Indanones, and Other Hemiindigoid Scaffolds: Medicinal Chemistry and Photopharmacology Perspectives.
Lazinski LM, Royal G, Robin M, Maresca M, Haudecoeur R.
J Med Chem (2022) 65 : 12594 -12625
PubMed 36126323 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.40 5.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2018039 1 5.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2018039 IC50 = 4000.0 nM 5.40