Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5239289

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to GST tagged AR LBD (unknown orign) by radioligand binding assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Androgen receptor (CHEMBL1871)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A Comprehensive Overview of Small-Molecule Androgen Receptor Degraders: Recent Progress and Future Perspectives.
Ha S, Luo G, Xiang H.
J Med Chem (2022) 65 : 16128 -16154
PubMed 36459083 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 6.84 7.11

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4584527 1 7.11
CHEMBL4444904 1 6.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4584527 Ki = 78.06 nM 7.11
CHEMBL4444904 Ki = 267.39 nM 6.57