Assay Detail
Functional
CHEMBL5241900
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human U-937 cells assessed as reduction cell viability incubated for 48 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U-937 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Quinoline anticancer agents active on DNA and DNA-interacting proteins: From classical to emerging therapeutic targets.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.13 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5269562 | — | — | 1 | 6.40 |
| CHEMBL5285340 | — | — | 1 | 6.16 |
| CHEMBL5286148 | — | — | 1 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5269562 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL5285340 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL5286148 | — | IC50 | = | 1500.0 | nM | 5.82 |