Compound Detail
CHEMBL5286148
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Basic Information
| ChEMBL ID | CHEMBL5286148 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DCNIXVVUMMQHRG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
481.6
MW (Da)
7.52
ALogP
5
HBA
3
HBD
78.9
PSA (Ų)
0.23
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| U-937 CHEMBL612794 | IC50 | 5.82 | 5.82 | 1500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| U-937 | IC50 | = | 1500.0 | nM | 5.82 | Antiproliferative activity against human U-937 cells assessed as reduction cell ... | 34052677 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34052677 | 10.1016/j.ejmech.2021.113555 | U-937 | 1 |
Data from ChEMBL 36 via Core Engine