Assay Detail
Binding
CHEMBL5242005
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Antagonist activity at human LPA1 receptor
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Lysophosphatidic acid (LPA) receptor modulators: Structural features and recent development.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.97 | 7.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL272087 | — | — | 1 | 7.02 |
| CHEMBL5279659 | — | — | 1 | 7.00 |
| CHEMBL5288440 | — | — | 1 | 7.00 |
| CHEMBL5283539 | — | — | 1 | 7.00 |
| CHEMBL5280108 | — | — | 1 | 7.00 |
| CHEMBL5285576 | — | — | 1 | 7.00 |
| CHEMBL5275262 | — | — | 1 | 7.00 |
| CHEMBL3932828 | — | — | 1 | 6.96 |
| CHEMBL5272430 | — | — | 1 | 6.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL272087 | — | IC50 | = | 95.0 | nM | 7.02 |
| CHEMBL5279659 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL5288440 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL5283539 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL5280108 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL5285576 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL5275262 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL3932828 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL5272430 | — | IC50 | = | 190.0 | nM | 6.72 |