Assay Detail
Binding
CHEMBL5242301
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PLK2 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase PLK2 (CHEMBL5938) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
A comprehensive overview of β-carbolines and its derivatives as anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.33 | 5.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5269742 | — | — | 1 | 5.42 |
| CHEMBL2164716 | — | — | 1 | 5.37 |
| CHEMBL5280383 | — | — | 1 | 5.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5269742 | — | IC50 | = | 3820.0 | nM | 5.42 |
| CHEMBL2164716 | — | IC50 | = | 4300.0 | nM | 5.37 |
| CHEMBL5280383 | — | IC50 | = | 6450.0 | nM | 5.19 |