Assay Detail
Functional
CHEMBL5242736
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Cytotoxicity against human BT-549 cells assessed as cell growth inhibition incubated for 48 hrs by WST-1 assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | BT-549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Plant isoquinoline alkaloids: Advances in the chemistry and biology of berberine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.52 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL400092 | LYCORINE | — | 1 | 6.52 |
| CHEMBL401114 | (+)-HAEMANTHAMINE | — | 1 | 6.52 |
| CHEMBL465820 | — | — | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL400092 | LYCORINE | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL401114 | (+)-HAEMANTHAMINE | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL465820 | — | IC50 | = | 300.0 | nM | 6.52 |