Assay Detail
Functional
CHEMBL5243296
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Anticancer activity against human DLD-1 cells assessed as cell growth inhibition incubated for 24 hrs
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DLD-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Insights into the recent progress in the medicinal chemistry of pyranopyrimidine analogs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.09 | 6.84 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5268029 | — | — | 1 | 6.84 |
| CHEMBL5267417 | — | — | 1 | 6.22 |
| CHEMBL5284873 | — | — | 1 | 5.67 |
| CHEMBL17289 | CHS-828 | 1.0 | 1 | 5.63 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5268029 | — | IC50 | = | 146.0 | nM | 6.84 |
| CHEMBL5267417 | — | IC50 | = | 606.0 | nM | 6.22 |
| CHEMBL5284873 | — | IC50 | = | 2128.0 | nM | 5.67 |
| CHEMBL17289 | CHS-828 | IC50 | = | 2315.0 | nM | 5.63 |