Assay Detail
Functional
CHEMBL5243299
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Anticancer activity against human HONE1 cell line assessed as cell growth inhibition incubated for 24 hrs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HONE1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Insights into the recent progress in the medicinal chemistry of pyranopyrimidine analogs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.93 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL17289 | CHS-828 | 1.0 | 1 | 7.82 |
| CHEMBL5267417 | — | — | 1 | 6.70 |
| CHEMBL5268029 | — | — | 1 | 6.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL17289 | CHS-828 | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL5267417 | — | IC50 | = | 201.0 | nM | 6.70 |
| CHEMBL5268029 | — | IC50 | = | 536.0 | nM | 6.27 |