Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5245337

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human Leukemia cell assessed as reduction in cell viability
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Leukemia cell
Confidence 1 — Organism
Curated By Autocuration

Target

Leukemia cell (CHEMBL614844)
Type CELL-LINE
Organism Homo sapiens

Publication

Artemisinin-derived hybrids and their anticancer activity.
Gao F, Sun Z, Kong F, Xiao J.
Eur J Med Chem (2020) 188 : 112044 -112044
PubMed 31945642 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.08 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5273139 1 7.00
CHEMBL361497 ARTESUNATE 4.0 1 5.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5273139 IC50 = 100.0 nM 7.00
CHEMBL361497 ARTESUNATE IC50 = 6887.0 nM 5.16