Assay Detail
Functional
CHEMBL5245602
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human DLD-1 cells assessed as cell growth inhibition measured after 72 hrs
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DLD-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Diarylpentanoids with antitumor activity: A critical review of structure-activity relationship studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.83 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL598509 | — | — | 1 | 6.00 |
| CHEMBL598465 | — | — | 1 | 6.00 |
| CHEMBL600786 | — | — | 1 | 6.00 |
| CHEMBL601000 | — | — | 1 | 6.00 |
| CHEMBL5282911 | — | — | 1 | 6.00 |
| CHEMBL472887 | — | — | 1 | 5.00 |
| CHEMBL5273972 | — | — | 1 | - |
| CHEMBL598507 | — | — | 1 | - |
| CHEMBL274993 | 2,6-DIBENZYLIDENECYCLOHEXANONE | — | 1 | - |
| CHEMBL5271995 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL598509 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL598465 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL600786 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL601000 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL5282911 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL472887 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL5273972 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL598507 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL274993 | 2,6-DIBENZYLIDENECYCLOHEXANONE | IC50 | > | 50000.0 | nM | - |
| CHEMBL5271995 | — | IC50 | > | 50000.0 | nM | - |