Assay Detail
Binding
CHEMBL5246052
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Aurora B (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent researches for dual Aurora target inhibitors in antitumor field.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.83 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5278077 | — | — | 1 | 7.85 |
| CHEMBL191003 | JNJ-7706621 | — | 1 | 7.82 |
| CHEMBL2170414 | — | — | 1 | 7.81 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5278077 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL191003 | JNJ-7706621 | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL2170414 | — | IC50 | = | 15.6 | nM | 7.81 |