Assay Detail
Binding
CHEMBL5247025
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at muscarinic M2 receptor (unknown origin) assessed as inhibition constant
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Geminal Diheteroatomic Motifs: Some Applications of Acetals, Ketals, and Their Sulfur and Nitrogen Homologues in Medicinal Chemistry and Drug Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.53 | 11.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL76164 | — | — | 1 | 11.00 |
| CHEMBL74141 | — | — | 1 | 9.29 |
| CHEMBL92569 | — | — | 1 | 8.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL76164 | — | Ki | = | 0.01 | nM | 11.00 |
| CHEMBL74141 | — | Ki | = | 0.51 | nM | 9.29 |
| CHEMBL92569 | — | Ki | = | 5.0 | nM | 8.30 |