Assay Detail
Functional
CHEMBL5247124
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV-1 LAV
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Geminal Diheteroatomic Motifs: Some Applications of Acetals, Ketals, and Their Sulfur and Nitrogen Homologues in Medicinal Chemistry and Drug Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 6.65 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL885 | EMTRICITABINE | 4.0 | 1 | 8.10 |
| CHEMBL18314 | — | — | 1 | 6.70 |
| CHEMBL89554 | — | — | 1 | 6.08 |
| CHEMBL141 | LAMIVUDINE | 4.0 | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL885 | EMTRICITABINE | EC50 | = | 8.0 | nM | 8.10 |
| CHEMBL18314 | — | EC50 | = | 200.0 | nM | 6.70 |
| CHEMBL89554 | — | EC50 | = | 840.0 | nM | 6.08 |
| CHEMBL141 | LAMIVUDINE | EC50 | = | 2000.0 | nM | 5.70 |